Design of polymeric and hybrid nanostructures for drug delivery and theranostic applications
- Villar Álvarez, Eva María
- Pablo Taboada Antelo Director
- Silvia Barbosa Fernández Co-director
Universidade de defensa: Universidade de Santiago de Compostela
Fecha de defensa: 14 de setembro de 2018
- Jacqueline Forcada Garcia Presidente/a
- Gerardo Prieto Estévez Secretario/a
- Giuseppe Lazzara Vogal
Tipo: Tese
Resumo
Nanomedicine attempts to solve some of the main limitations of materials and techniques currently used in clinical practice. To do that, the design and fabrication of the so-called nanoplatforms has been envisaged. These allow the encapsulation, protection and delivery of bioactive molecules but also provide new functionalities thanks to their exceptional properties. This work is focused on the design of biocompatible polymeric nanoparticles to enable the administration of different drugs, single or in combination, for the treatment of common diseases as diabetes, infections or tumors. In addition, several multifunctional hybrid nanoplatforms have been designed for cancer theranostics and combinatorial therapeutics.