Enfermedades reumáticas en la adolescencia. Artritis idiopática juvenil. Conectivopatías
- Garulo, D. Clemente
- Mateos, L. León
- Robledillo, J.C. López
ISSN: 0304-5412
Year of publication: 2018
Series: 12
Issue: 61
Pages: 3588-3600
Type: Article
More publications in: Medicine: Programa de Formación Médica Continuada Acreditado
Abstract
These are diseases that are caused by the inflammation of diverse body structures due to deregulation of the immune system. The signs and symptoms can be non-specific and the onset can be over weeks or months. While juvenile idiopathic arthritis principally involves the joints, a disorder in multiple organs of no apparent cause associated with specific clinical manifestations (malar rash, Gottron's papules, Raynaud's phenomenon, sclerodactyly) should arouse suspicion of a connective tissue disease. Diagnosis is made through a combination of clinical and analytical criteria such as the presence of antinuclear antibodies, rheumatoid factor or genetic markers such as HLA B27. It is important to start appropriate treatment as promptly as possible, which includes corticosteroids, immunosuppressive drugs and biological treatments.
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