Uso de voriconazol tópico en queratitis por alternaria

  1. B. De-Domingo-Barón
  2. T. Rodríguez-Ares
  3. R. Touriño-Peralba
  4. F. Pardo-Sánchez
  5. P. Romero-Jung
  6. M. Barcia
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2008

Volume: 83

Issue: 8

Pages: 493-496

Type: Article

DOI: 10.4321/S0365-66912008000800007 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Clinical case: A 38-year-old man with fungal Alternaria keratitis was referred from another hospital 25 days after post-traumatic penetrating keratoplastia surgery on his right eye. We commenced treatment with topical voriconazole and the condition resolved. Discussion: Fungal Alternaria keratitis is rare, and treatment is difficult because the clinical response does not correlate well with the antibiotic in vitro sensitivity of the fungus. Clinical cases need to be diagnosed and treated quickly if visual loss is to be avoided. The combination of topical and systemic voriconazole has been shown to be an effective treatment for this condition