Química receptor-sustrato y procesos de autoclaificación basados en metalociclos funcionalizados

Abstract

This dissertation is divided in three parts. In the first part, we have studied the ability of a 2,7-diazapyrenium-based Pd(II) dinuclear metallacycle to complex aromatic guests in aqueous media. These inclusion complexes are favoured by π-π and C-H···π interactions as well as by the hydrophobic effect. All of these aggregates were characterized by 1D and 2D NMR and single crystal X-ray crystallography. Furthermore, the thermodynamic and kinetic parameters of the host-guest complexation have been also explored. The second part of this work is focused on the synthesis of new 4,4´-bipyridinium/2,7-diazapyrenium-based ligands owning several different functional groups. Self-assembly of these ligands with Pd(II) and Pt(II) metal centers, resulted in a series of a new functionalized metallacycles. The groups posed into the ligands do not interfere in the self-assembly processes. The ability of these new functionalized metallacycles to complex aromatic guests in water has been also studied. Finally, we have explored the synthesis of supramolecular systems designed to produce pseudo[1]rotaxanes in aqueous media. These supramolecules were obtained by assembly of ternary mixtures of complementary ligands and Pd(II) and Pt(II) centers. The pseudo[1]rotaxanes are the result of integrative social self-sorting, where, the formation of the species increases the enthalpic and entropic gain of the system.