Influencia de la ingesta de ácidos grasos omega-3, en la evolución de la inflamación presente en la artritis reumatoide.

  1. Susana Viñas Diz 1
  2. Mª José López Armada 2
  1. 1 Departamento de Fisioterapia, Medicina y Ciencias Biomédicas. Universidad de A Coruña. La Coruña. España
  2. 2 Grupo de Investigación en Envejecimiento e Inflamación, Instituto de Investigación Biomédica A Coruña (INIBIC). La Coruña. España
Journal:
Nutrición clínica y dietética hospitalaria

ISSN: 0211-6057

Year of publication: 2021

Volume: 41

Issue: 3

Pages: 111-122

Type: Article

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More publications in: Nutrición clínica y dietética hospitalaria

Abstract

Introduction: Due to a greater knowledge of the mecha-nisms involved in inflammatory processes, currently in thefield of rheumatoid arthritis (RA) there is a great interest inknowing if the lifestyle (diet, and / or physical exercise) in-fluences the development of the disease, since there are in-dications that nutrition may play an important role in the pre-disposition and / or resolution of the inflammatory process insaid pathology.Objectives:- Explain the effects of omega-3 fatty acids on the symp-toms present in patients with RA. We will analyze whet-her it is possible to influence inflammation, only by sup-plementing with omega-3, or it is necessary to carry outother dietary actions- Identify which are the most studied study variables whensupplementing with omega-3. - Identify which are the most used omega-3 doses, as wellas where the fatty acids that are supplemented comefrom.Methods: A bibliographic search was carried out in 6 da-tabases (Cochrane Library, Pubmed, Scopus, Web of Science(Wos), CINAHL, and SPORTDiscus), in December-January2021. The search terms were: “arthritis rheumatoid or rheu-matoid arthritis ”and“ fatty acids omega 3 or omega 3 fattyacids ”. The search has been restricted to meta-analysis, sys-tematic review, reviews, clinical trial, controlled and / or ran-domized clinical trial. Studies published in the last 5 years(2015-2020) carried out in humans, and published in Englishor Spanish. Results: 240 results were initially obtained. 70 articleswere eliminated for being duplicates, and 120 articles for notmeeting the inclusion criteria. 50 full-text articles were read,of which 30 articles were finally selected.Discussion / conclusions: In RA, supplemented omega-3have been shown to have beneficial effects on clinical parame-ters of the disease: decrease in the number of painful and swo-llen joints, improvements in morning stiffness, in grip strength,in the evaluation overall of the disease assessed by the doctor,and reduction of the use of AINEs and other drugs.

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