Síndrome metabólico y litiasis urinaria de ácido úrico
- Lancina Martín, Juan Alberto
- Portela Pereira, Paula
- Vázquez-Martul Pazos, Darío
- López García, Daniel
- Sánchez Merino, José María
- Aller Rodríguez, Marcos
- Lamas Meilán, Cipriano
- Rey Fraga, Dolores
ISSN: 0365-7965
Year of publication: 2013
Tome: 98
Issue: 788
Pages: 22-26
Type: Article
More publications in: Actualidad médica
Abstract
Introduction: Epidemiologic studies have reported association between urolithiasis with cardiovascular diseases as type 2 diabetes, arterial hypertension and metabolic syndrome. This study was conducted to examine the proportion of metabolic syndrome in patients with uric acid stones. Materials and methods: 71 patients with uric acid stones were included, 46 males and 25 females, mean age was 62.4 years. Diagnosis of stone laterality and localization was confirmed by ultrasonography and/or computerized axial tomography. Metabolic syndrome definition was made according of criteria proposed by NCEP-ATP III. Chi- square test with correction of Yates was used to assess the statistical significance of differences. Results: Metabolic syndrome were observed in 49 patients (69.0%), significantly higher than 31% rate reported for Spanish population (p<0.0001). In addition, it was found decrease serum HDL-cholesterol in 59 patients (83.1%), abdominal obesity in 48 (67.8%), high blood pressure in 46 (64.8%), hypertrigliceremia in 39 (54.9%) and hyperglycemia in 31 (43.7%), all of that was significantly more frequent than data reported for Spanish population. Conclusions: Uric acid stones were positively associated with metabolic syndrome, as well as for each of the factors of metabolic syndrome, with rates higher than registered in Spanish population.