Espectro clínico de la Enfermedad de Castleman
ISSN: 0304-4866, 1989-3922
Year of publication: 2014
Volume: 75
Issue: 4
Pages: 191-194
Type: Article
More publications in: Galicia Clínica
Sustainable development goals
Abstract
Castleman�s disease (CD) is a rare hematological disease characterized by hyperplasia of lymphoid nodules with two distinct histological and clinical patterns: hyaline - vascular which is usually single-center, low and aggressive behavior which gets exeresis healing in most of cases. The plasma cell variant is more aggressive clinical presentation mimics highgrade lymphomas and requires chemotherapy to eradicate. Play an etiopathogenic role HHV -8 and IL -6 and IL -1 cytokines. New drugs based on the blockade of IL -6 or its receptors have recently proved useful in the control of the disease. We present cases representing the spectrum of CD.