Criterios de extracción de muestra en situaciones especiales del cribado neonatal. Revisión
- Magdalena Vila Vidal
- Rosa María López Galera
- Yolanda González Irazabal
- Carmen Delgado Pecellín
- D. Rausell 1
- Daisy Castiñeiras
- José María Egea Mellado
- Hugo Rocha 1
- Raquel Yahyaoui
- Teresa Rodríguez 1
- Vanesa Escribano Hernández 1
- Olaia Rodríguez Fraga
- María Dolores Bóveda Fontán 1
- José Luis Marín Soria
- 1 Sección de Metabolopatías y Cribado Neonatal, Servicio de Análisis Clínicos, Hospital Universitario Son Espases, Palma de Mallorca, Illes Balears, España
ISSN: 1888-4008
Year of publication: 2019
Volume: 12
Issue: 4
Pages: 189-195
Type: Article
More publications in: Revista del laboratorio clínico
Abstract
The most significant breakthrough in the newborn screening (NBS) programs was the introduction of the tandem mass spectrometry (MS-MS) to the laboratory, which makes it possible to detect multiple disorders. However, it is difficult to choose the ideal time for the specimen collection, particularly in preterm, low birth weight, and sick newborns. The aim of this study was to revise the protocols, in national and international programs for specimen collection in these newborns. Data were collected from web pages of public health, internet searches, and contact with the laboratories. The results showed a great disparity in criteria for a new specimen collection, as well as among different centres within a country. It has been difficult to obtain this information from many countries in Africa, Asia, and Latin America. Although an increasing number of laboratories follow the recommendations of the Clinical and Laboratory Standards Institute or other international guidelines, the increased cost involved makes standardisation difficult.