Histiocitosisa propósito de dos casos clínicos
- Helena Pérez Tato
- Paula Buyo Sánchez
- Ana Belén Alas Barbeito
- G. Muñoz García
- Mercedes Álvarez-Buylla Blanco
- Liliana Filipa Invencio da Costa
ISSN: 0001-6640
Ano de publicación: 2020
Volume: 78
Número: 3-4
Páxinas: 175-177
Tipo: Artigo
Outras publicacións en: Acta pediátrica española
Resumo
Introduction: Histiocytosis is an uncommon pathology, consisting of an uncontrolled proliferation and accumulation of Langerhans cells. It most often affects the bones with an unspecified clinical presentation. The amount and kind of affected organs is what marks the classification and the necessity of chemotherapy treatment in this pathology. Clinical case 1: We present a case of histiocytosis of bone initially interpreted as an hematoma. Clinical case 2: We present a case of histiocytosis of bone which starts as an otorrhea lasting 4 weeks. It was diagnosed at the beginning with purulent otitis. Conclusions: Despite its infrequency, histiocytosis is a disease that should be considered when assessing the persistence of lesions, tumors or pathology that may initially seem banal. Advances in the knowledge of the pathogenesis of this disease and the discovery of the genes involved open the way to new targeted therapies.