Tubérculo coroideo asintomático en un paciente con enfermedad de Crohn en tratamiento con adalimumab
- V.M. Asensio-Sánchez
- L. Díaz-Cabanas
- A. Martín-Prieto
- B. Haro-Álvarez
ISSN: 0365-6691
Year of publication: 2018
Volume: 93
Issue: 3
Pages: 147-150
Type: Article
More publications in: Archivos de la Sociedad Española de Oftalmologia
Sustainable development goals
Abstract
Introduction Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. Case report The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy. Discussion Choroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab.