Pérdida de peso en pacientes con sobrepeso u obesidad con artrosis de rodilla
ISSN: 2171-9020
Year of publication: 2018
Issue Title: Validez del TAC coronario 5 años
Volume: 2
Issue: 41
Type: Article
More publications in: MPG Journal
Abstract
The objective of this study is to determine the dose response effect of weight loss on clinical and mechanistic outcomes in overweight and obese adults with knee osteoarthritis (OA). Most randomized controlled weight loss trials in older overweight and obese adults with knee OA showed weight reduction of 5–10% after 1–2 years. Data from the National Weight Control Registry indicate that some patients lose more than twice that amount and maintain the reduction. However, whether weight loss of this magnitude can be achieved non-surgically under randomized clinical trial conditions, and whether there is any benefit beyond what has been shown with 10% weight loss in a population of patients with knee OA, are unknown. This article hypothesized that participants who lost ≥20% of baseline body weight would have significantly reduced pain, knee joint loads, and systemic inflammation as well as improved function and health-related quality of life (HRQoL) compared with participants who lost <5%, 5–9.9%, or 10–19.9% of their baseline body weight.
Bibliographic References
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