Epidemiology, oncologic results and risk stratification model for metachronous peritoneal metastases after surgery for pT4 colon cancers: results from an observational retrospective multicentre long-term follow-up study

  1. Cerdán-Santacruz, C.
  2. Cano-Valderrama, Ó. 1
  3. Peña Ros, E.
  4. Serrano del Moral, Á.
  5. Pereira Pérez, F.
  6. Flor Lorente, B.
  7. Biondo, S.
  8. Rihuete Caro, Cristina
  9. Jiménez de los Galanes Marchán, Santos
  10. Fernández López, Fernando
  11. Paz Novo, Manuel
  12. Blanco Antona, Francisco
  13. Noguera Aguilar, José Francisco
  14. Taboada Ameneiro, María
  15. Moncada Iribarren, Enrique
  16. Aldrey Cao, Inés
  17. Núñez Fernández, Sandra
  18. Villarejo, Pedro
  19. Guadalajara Labajo, Héctor
  20. Uribe Quintana, Natalia
  21. Balciscueta Coltell, Zutoia
  22. Beltrán de Heredia, Juan
  23. de Andrés Asenjo, Beatriz
  24. Nuño Iglesias, Christian
  25. Lora Cumplido, Paola
  26. Bollo Rodríguez, Jesús
  27. Pascual Damieta, Marta
  28. Etxart Lopetegi, Ane
  29. Ambrona Zafra, David
  30. Pérez Farré, Silvia
  31. Richart Aznar, José Manuel
  32. Peris Tomás, Nuria
  33. Estaire Gómez, Mercedes
  34. Garcia Santos, Esther
  35. Calero Amaro, Alicia
  36. Sánchez Guillén, Luis
  37. Jiménez Carneros, Virginia
  38. Valle Rubio, Ainhoa
  39. Obregón Reina, Rosángela
  40. Dujovne Lindenbaum, Paula
  41. de San Pio Carvajal, Eduardo
  42. Sagarra Cebolla, Elena
  43. Frago Montanuy, Ricardo
  44. Mayol Oltra, Araceli
  45. Boldó Roda, Enrique
  46. Carrasco Campos, Joaquín
  47. Titos García, Alberto
  48. Turienzo Santos, Estrella
  49. Cifrián Canales, Isabel
  50. Prada, Arancha
  51. Carmona Agúndez, María
  52. Artiles Armas, Manuel
  53. Arencibia Pérez, Beatriz
  54. Blanco Terés, Lara
  55. Gancedo Quintana, Álvaro
  56. Rueda Orgaz, José Antonio
  57. Ochando Cerdán, Federico
  58. Díez Alonso, Manuel
  59. Gómez Sanz, Remedios
  60. Ocaña Jiménez, Juan
  61. Galindo Álvarez, Julio
  62. Luna Díaz, María del Mar
  63. Asensio Díaz, Enrique
  64. Labarga Rodríguez, Fernando
  65. Allué, Marta
  66. Utrilla Fornals, Alejandra
  67. Segura Jiménez, Inmaculada
  68. Conde Muíño, Raquel
  69. Fernández Miguel, Tamara
  70. Vicente Rodríguez, Irune
  71. Conde Rodríguez, María
  72. Ramírez Ruiz, Laura
  73. Moreno Flores, Beatriz
  74. Camacho Dorado, Cristina
  75. Torres Melero, Juan
  76. Lorenzo Liñán, Miguel
  77. Labalde Martínez, María
  78. García Borda, Francisco Javier
  79. Álvarez Sarrado, Eduardo
  80. Concepción Martín, Vanessa
  81. Díaz López, Carmen
  82. Parra Baños, Pedro A.
  83. Peña Ros, Emilio
  84. Amillo Zaragüeta, Mireia
  85. Aurazo, Orlando
  86. Alías Jiménez, David
  87. Franco Herrera, Rocío
  88. Ramos Bonilla, Antonio
  89. Pérez González, Marta
  90. Pérez Sánchez, Asunción
  91. Valdés Hernández, Javier
  92. González Sánchez, Laura
  93. López-Tomasetti Fernández, Eudaldo
  94. Fernández Mancilla, Carlos
  95. González Prado, Cristina
  96. Cabriada García, Guillermo
  97. Collaborating group for the study of metachronous peritoneal metastases of pT4 colon cancer
  98. Show all authors +
  1. 1 Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
Journal:
Techniques in Coloproctology

ISSN: 1123-6337,  1128-045X

Year of publication: 2023

Type: Article

DOI: 10.1007/S10151-023-02816-Z GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Techniques in Coloproctology

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Bibliographic References

  • Klaver CEL, Wisselink DD, Punt CJA et al (2019) Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial. Lancet Gastroenterol Hepatol 4(10):761–770
  • Quenet F, Elias D, Roca L et al (2021) Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol 22(2):256–266
  • Bastiaenen VP, Klaver CEL, Kok NFM et al (2019) Second and third look laparoscopy in pT4 colon cancer patients for early detection of peritoneal metastases; the COLOPEC 2 randomized multicentre trial. BMC Cancer 19(1):254
  • Perez RO, Mattacheo A, Tanis PJ (2021) Prophylactic HIPEC in high-risk colorectal cancer: do we really need a randomized clinical trial to prove a “logical” hypothesis? Tech Coloproctol 25(6):659–660
  • Segelman J, Granath F, Holm T, Machado M, Mahteme H, Martling A (2012) Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer. Br J Surg 99(5):699–705
  • van Gestel YR, Thomassen I, Lemmens VE et al (2014) Metachronous peritoneal carcinomatosis after curative treatment of colorectal cancer. Eur J Surg Oncol 40(8):963–969
  • Hompes D, Tiek J, Wolthuis A et al (2012) HIPEC in T4a colon cancer: a defendable treatment to improve oncologic outcome? Ann Oncol 23(12):3123–3129
  • van Santvoort HC, Braam HJ, Spekreijse KR et al (2014) Peritoneal carcinomatosis in T4 colorectal cancer: occurrence and risk factors. Ann Surg Oncol 21(5):1686–1691
  • Brind’Amour A, Dube P, Tremblay JF et al (2020) Canadian guidelines on the management of colorectal peritoneal metastases. Curr Oncol 27(6):e621–e631
  • Shepherd NA, Baxter KJ, Love SB (1997) The prognostic importance of peritoneal involvement in colonic cancer: a prospective evaluation. Gastroenterology 112(4):1096–1102
  • Bastiaenen VP, Tanis PJ (2021) Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: the role of homogeneous, reliable assessment and confounders. Eur J Surg Oncol 47(10):2698–2699
  • Segelman J, Akre O, Gustafsson UO, Bottai M, Martling A (2014) Individualized prediction of risk of metachronous peritoneal carcinomatosis from colorectal cancer. Colorectal Dis 16(5):359–367
  • Klose J, Kloor M, Warschkow R et al (2021) Does side really matter? Survival analysis among patients with right-versus left-sided colon cancer: a propensity score-adjusted analysis. Ann Surg Oncol 28(5):2768–2778
  • Jessup J, Goldberg RM, Asare EA et al. AJCC cancer staging manual. Chapter 2017;20(20): 251–274
  • Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13(10):606–608
  • Peel AL, Taylor EW (1991) Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl 73(6):385–388
  • Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196
  • Wisselink DD, Klaver CEL, Hompes R, Bemelman WA, Tanis PJ (2020) Curative-intent surgery for isolated locoregional recurrence of colon cancer: review of the literature and institutional experience. Eur J Surg Oncol 46(9):1673–1682
  • von Elm E, Altman DG, Egger M et al (2007) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596):1453–1457
  • Bastiaenen VP, Aalbers AGJ, Arjona-Sanchez A et al (2021) Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: an international multicentre cohort study. Eur J Surg Oncol 47(9):2405–2413
  • Sammartino P, Sibio S, Biacchi D et al (2014) Long-term results after proactive management for locoregional control in patients with colonic cancer at high risk of peritoneal metastases. Int J Colorectal Dis 29(9):1081–1089
  • Jung F, Lee M, Doshi S et al (2021) Neoadjuvant therapy versus direct to surgery for T4 colon cancer: meta-analysis. Br J Surg 109(1):30–36
  • Honore C, Goere D, Souadka A, Dumont F, Elias D (2013) Definition of patients presenting a high risk of developing peritoneal carcinomatosis after curative surgery for colorectal cancer: a systematic review. Ann Surg Oncol 20(1):183–192
  • Elias D, Honore C, Dumont F et al (2011) Results of systematic second-look surgery plus HIPEC in asymptomatic patients presenting a high risk of developing colorectal peritoneal carcinomatosis. Ann Surg 254(2):289–293
  • Tan KL, Tan WS, Lim JF, Eu KW (2010) Krukenberg tumors of colorectal origin: a dismal outcome–experience of a tertiary center. Int J Colorectal Dis 25(2):233–238
  • Mayanagi S, Kashiwabara K, Honda M et al (2018) Risk factors for peritoneal recurrence in stage II to III colon cancer. Dis Colon Rectum 61(7):803–808
  • Biondo S, Galvez A, Ramirez E, Frago R, Kreisler E (2019) Emergency surgery for obstructing and perforated colon cancer: patterns of recurrence and prognostic factors. Tech Coloproctol 23(12):1141–1161
  • Noura S, Ohue M, Seki Y, Yano M, Ishikawa O, Kameyama M (2009) Long-term prognostic value of conventional peritoneal lavage cytology in patients undergoing curative colorectal cancer resection. Dis Colon Rectum 52(7):1312–1320
  • Honore C, Gelli M, Francoual J, Benhaim L, Elias D, Goere D (2017) Ninety percent of the adverse outcomes occur in 10% of patients: can we identify the populations at high risk of developing peritoneal metastases after curative surgery for colorectal cancer? Int J Hyperthermia 33(5):505–510
  • Goere D, Glehen O, Quenet F et al (2020) Second-look surgery plus hyperthermic intraperitoneal chemotherapy versus surveillance in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP-PRODIGE 15): a randomised, phase 3 study. Lancet Oncol 21(9):1147–1154