Meningitis criptocócica asociada a hidrocefalia en un paciente inmunocompetente

  1. Julián Castro Castro 1
  2. María Dolores Díaz López 1
  1. 1 Complexo Hospitalario Universitario de Ourense
    info

    Complexo Hospitalario Universitario de Ourense

    Orense, España

    ROR https://ror.org/04f1y4a64

Journal:
Anales del sistema sanitario de Navarra

ISSN: 1137-6627

Year of publication: 2024

Volume: 47

Issue: 1

Pages: 105-109

Type: Article

DOI: 10.23938/ASSN.1067 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Anales del sistema sanitario de Navarra

Abstract

Cryptococcal meningitis is an infrequent infection with high morbidity and mortality. Its presentation in immuno-competent patients is rare.We present the case of a 67-year-old male who was admitted for subacute symptoms of gait disturbance and urinary incontinence. Neurological examination revealed inability to stand and memory impairment. Cranial im-aging showed obstructive tetraventricular hydrocephalus with areas of gliosis in the cerebellar peduncles. Endo-scopic treatment of hydrocephalus was performed and cerebrospinal fluid samples taken revealing the growth of Cryptococcus neoformans. The patient improved with the endoscopic treatment and after completing intravenous antifungal therapy with liposomal amphotericin B and flu-conazole for ten weeks.Antifungals are used to treat cryptococcal meningitis in immunocompetent patients. On rare occasions, it presents with hydrocephalus, a situation that requires surgical treat-ment using cerebrospinal fluid diversions or endoscopic techniques.

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