Publications (103) Publications in which a researcher has participated

2024

  1. Stilbene-pyridazinone hybrids: design, synthesis and in vitro antiplatelet activity screening

    Bioorganic Chemistry, Vol. 150

2022

  1. Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents

    Molecules, Vol. 27, Núm. 23

  2. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity

    ACS Medicinal Chemistry Letters, Vol. 13, Núm. 3, pp. 463-469

2021

  1. Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors

    Bioorganic Chemistry, Vol. 115

  2. The new pharmacological chaperones pbxs increase α-galactosidase a activity in fabry disease cellular models

    Biomolecules, Vol. 11, Núm. 12

2020

  1. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy

    Bioorganic Chemistry, Vol. 104

2019

  1. Novel compounds of hybrid structure pyridazinone-coumarin as potent inhibitors of platelet aggregation

    Future medicinal chemistry, Vol. 11, Núm. 16, pp. 2051-2062

  2. Recent advances in the synthesis of phthalazin-1(2H)-one core as a relevant pharmacophore in medicinal chemistry

    European Journal of Medicinal Chemistry

2017

  1. Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

    European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11

2016

  1. Actividad letal de seis venenos de serpientes de importancia médica en el Ecuador

    Revista Ecuatoriana de Medicina y Ciencias Biológicas: REMCB, Vol. 37, Núm. 2, pp. 25-30

  2. Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2: H)-one derivatives as novel cholinesterase inhibitors

    RSC Advances, Vol. 6, Núm. 52, pp. 46170-46185

  3. Topological sub-structural molecular design (TOPS-MODE): a useful tool to explore key fragments of human A3adenosine receptor ligands

    Molecular Diversity, Vol. 20, Núm. 1, pp. 55-76

2015

  1. New platelet aggregation inhibitors based on pyridazinone moiety

    European Journal of Medicinal Chemistry, Vol. 94, pp. 113-122

  2. Phthalazin-1(2H)-one as a remarkable scaffold in drug discovery

    European Journal of Medicinal Chemistry, Vol. 97, Núm. 1, pp. 462-482

2013

  1. 2-Benzyl-5-methoxyisoindoline-1,3-dione

    Acta Crystallographica Section E: Structure Reports Online, Vol. 69, Núm. 10

  2. 4-[(tert-Butyldiphenylsilyloxy)methyl]pyridazin-3(2H)-one

    Acta Crystallographica Section E: Structure Reports Online, Vol. 69, Núm. 12

  3. 5-[(tert-Butyldiphenylsilyloxy)methyl]pyridazin-3(2H)-one

    Acta Crystallographica Section E: Structure Reports Online, Vol. 69, Núm. 12

2012

  1. Synthesis of a Greek tobacco lactonic natural product and its analogues

    Tetrahedron Letters, Vol. 53, Núm. 33, pp. 4293-4295

2011

  1. Synthesis and complete assignment of the 1H and 13C NMR spectra of 6-substituted and 2,6-disubstituted pyridazin-3(2H)-ones

    Magnetic Resonance in Chemistry, Vol. 49, Núm. 7, pp. 437-442

  2. Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors

    Journal of Medicinal Chemistry, Vol. 54, Núm. 20, pp. 7127-7137