Publicacións en colaboración con investigadores/as de Universidade Do Porto (24)

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  2. Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)

    Molecules, Vol. 28, Núm. 1

2022

  1. Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin

    Molecules, Vol. 27, Núm. 3

2021

  1. 7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation

    ChemMedChem, Vol. 16, Núm. 1, pp. 179-186

  2. Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors

    Bioorganic Chemistry, Vol. 108

  3. Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

    ACS Chemical Neuroscience, Vol. 12, Núm. 1, pp. 203-215

2020

  1. 3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?

    Bioorganic Chemistry, Vol. 101

  2. Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents

    ChemMedChem, Vol. 15, Núm. 6, pp. 532-538

  3. Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies

    Bioorganic Chemistry, Vol. 101

2019

  1. Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity

    ChemistrySelect, Vol. 4, Núm. 26, pp. 7698-7703

2017

  1. MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations

    MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796

  2. Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

    European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11

2016

  1. Computational Drug Target Screening through Protein Interaction Profiles

    Scientific Reports, Vol. 6

2015

  1. 3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

    ChemMedChem, Vol. 10, Núm. 12, pp. 2071-2079

2014

  1. Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

    Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383

2013

  1. Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors

    European Journal of Medicinal Chemistry, Vol. 59, pp. 75-90

2012

  1. 8-Substituted 3-Arylcoumarins as Potent and Selective MAO-B Inhibitors: Synthesis, Pharmacological Evaluation, and Docking Studies

    ChemMedChem, Vol. 7, Núm. 3, pp. 464-470

  2. Exploring nitrostyrene as a scaffold for a new class a of monoamine oxidase inhibitors

    Letters in Drug Design and Discovery, Vol. 9, Núm. 10, pp. 958-961

2011

  1. Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 21, Núm. 2, pp. 707-709

  2. Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

    Journal of Medicinal Chemistry, Vol. 54, Núm. 14, pp. 5165-5173