María Josefa
Guerra Seijas
Publicacións (68) Publicacións de María Josefa Guerra Seijas
2020
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Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, Which Induces Vulnerability to Oxidative Stress and Neurodegeneration
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 75, Núm. 3, pp. 416-424
2018
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Aging-related dysregulation in enteric dopamine and angiotensin system interactions: Implications for gastrointestinal dysfunction in the elderly
Oncotarget, Vol. 9, Núm. 13, pp. 10834-10846
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Bidirectional Neural Interaction Between Central Dopaminergic and Gut Lesions in Parkinson’s Disease Models
Molecular Neurobiology, Vol. 55, Núm. 9, pp. 7297-7316
2017
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Brain renin-angiotensin system and microglial polarization: Implications for aging and neurodegeneration
Frontiers in Aging Neuroscience, Vol. 9, Núm. MAY
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Dopamine modulates astroglial and microglial activity via glial renin-angiotensin system in cultures
Brain, Behavior, and Immunity, Vol. 62, pp. 277-290
2016
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Menopause and Parkinson's disease. Interaction between estrogens and brain renin-angiotensin system in dopaminergic degeneration
Frontiers in Neuroendocrinology, Vol. 43, pp. 44-59
2015
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Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation
GLIA, Vol. 63, Núm. 3, pp. 466-482
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Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinsons Disease
Neuroscientist, Vol. 21, Núm. 6, pp. 616-629
2014
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Effect of chronic treatment with angiotensin type 1 receptor antagonists on striatal dopamine levels in normal rats and in a rat model of Parkinson's disease treated with l-DOPA
Neuropharmacology, Vol. 76, Núm. PART A, pp. 156-168
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Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death
Neuropharmacology, Vol. 85, pp. 1-8
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Microglial TNF-α mediates enhancement of dopaminergic degeneration by brain angiotensin
GLIA, Vol. 62, Núm. 1, pp. 145-157
2013
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Brain angiotensin regulates iron homeostasis in dopaminergic neurons and microglial cells
Experimental Neurology, Vol. 250, pp. 384-396
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Dopaminergic degeneration is enhanced by chronic brain hypoperfusion and inhibited by angiotensin receptor blockage
Age, Vol. 35, Núm. 5, pp. 1675-1690
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Inhibition of Rho kinase mediates the neuroprotective effects of estrogen in the MPTP model of Parkinson's disease
Neurobiology of Disease, Vol. 58, pp. 209-219
2012
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Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
Neurobiology of Aging, Vol. 33, Núm. 1, pp. 204.e1-204.e11
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Brain angiotensin and dopaminergic degeneration: Relevance to Parkinson’s disease
American Journal of Neurodegenerative Diseases, Vol. 1, Núm. 3, pp. 226-244
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Dopaminergic neuroprotection of hormonal replacement therapy in young and aged menopausal rats: Role of the brain angiotensin system
Brain, Vol. 135, Núm. 1, pp. 124-138
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Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: Effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease
Journal of Neuroinflammation, Vol. 9
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Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors
Neurobiology of Disease, Vol. 47, Núm. 2, pp. 268-279
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Mitochondrial ATP-sensitive potassium channels enhance angiotensin-induced oxidative damage and dopaminergic neuron degeneration. Relevance for aging-associated susceptibility to Parkinson's disease
Age, Vol. 34, Núm. 4, pp. 863-880