Begoña
Villar Cheda
Universidade de Santiago de Compostela
Santiago de Compostela, EspañaPublications in collaboration with researchers from Universidade de Santiago de Compostela (41)
2024
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Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission
npj Parkinson's Disease, Vol. 10, Núm. 1
2022
2021
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Nadph-oxidase, rho-kinase and autophagy mediate the (Pro)renin-induced pro-inflammatory microglial response and enhancement of dopaminergic neuron death
Antioxidants, Vol. 10, Núm. 9
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The intracellular renin-angiotensin system: Friend or foe. Some light from the dopaminergic neurons
Progress in Neurobiology, Vol. 199
2020
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Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, Which Induces Vulnerability to Oxidative Stress and Neurodegeneration
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 75, Núm. 3, pp. 416-424
2018
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Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans
Molecular Neurobiology, Vol. 55, Núm. 7, pp. 5847-5867
2017
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Insulin-like growth factor-1 and neuroinflammation
Frontiers in Aging Neuroscience
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The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system
Cell death & disease, Vol. 8, Núm. 9, pp. e3044
2016
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Aging-related Increase in Rho Kinase Activity in the Nigral Region is Counteracted by Physical Exercise
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 71, Núm. 10, pp. 1254-1257
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Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
Cell Death and Disease, Vol. 7, Núm. 10
2015
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Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinsons Disease
Neuroscientist, Vol. 21, Núm. 6, pp. 616-629
2014
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Aging-related dysregulation of dopamine and angiotensin receptor interaction
Neurobiology of Aging, Vol. 35, Núm. 7, pp. 1726-1738
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Effect of chronic treatment with angiotensin type 1 receptor antagonists on striatal dopamine levels in normal rats and in a rat model of Parkinson's disease treated with l-DOPA
Neuropharmacology, Vol. 76, Núm. PART A, pp. 156-168
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Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death
Neuropharmacology, Vol. 85, pp. 1-8
2013
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Dopamine-Angiotensin interactions in the basal ganglia and their relevance for Parkinson's disease
Movement Disorders, Vol. 28, Núm. 10, pp. 1337-1342
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Expression of angiotensinogen and receptors for angiotensin and prorenin in the monkey and human substantia nigra: An intracellular renin-angiotensin system in the nigra
Brain Structure and Function, Vol. 218, Núm. 2, pp. 373-388
2012
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Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
Neurobiology of Aging, Vol. 33, Núm. 1, pp. 204.e1-204.e11
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Brain angiotensin and dopaminergic degeneration: Relevance to Parkinson’s disease
American Journal of Neurodegenerative Diseases, Vol. 1, Núm. 3, pp. 226-244
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Dopaminergic neuroprotection of hormonal replacement therapy in young and aged menopausal rats: Role of the brain angiotensin system
Brain, Vol. 135, Núm. 1, pp. 124-138
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Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors
Neurobiology of Disease, Vol. 47, Núm. 2, pp. 268-279