Tubérculo coroideo asintomático en un paciente con enfermedad de Crohn en tratamiento con adalimumab

  1. V.M. Asensio-Sánchez
  2. L. Díaz-Cabanas
  3. A. Martín-Prieto
  4. B. Haro-Álvarez
Revista:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Ano de publicación: 2018

Volume: 93

Número: 3

Páxinas: 147-150

Tipo: Artigo

DOI: 10.1016/J.OFTAL.2017.06.009 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Archivos de la Sociedad Española de Oftalmologia

Obxectivos de Desenvolvemento Sustentable

Resumo

Introduction Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. Case report The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy. Discussion Choroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab.