BIOILS
Universidade de Santiago de Compostela
Santiago de Compostela, EspañaPublications in collaboration with researchers from Universidade de Santiago de Compostela (38)
2024
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Stilbene-pyridazinone hybrids: design, synthesis and in vitro antiplatelet activity screening
Bioorganic Chemistry, Vol. 150
2022
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Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents
Molecules, Vol. 27, Núm. 23
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Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity
ACS Medicinal Chemistry Letters, Vol. 13, Núm. 3, pp. 463-469
2021
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Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors
Bioorganic Chemistry, Vol. 115
2020
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Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy
Bioorganic Chemistry, Vol. 104
2019
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Novel compounds of hybrid structure pyridazinone-coumarin as potent inhibitors of platelet aggregation
Future medicinal chemistry, Vol. 11, Núm. 16, pp. 2051-2062
2017
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Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors
European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11
2016
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Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2: H)-one derivatives as novel cholinesterase inhibitors
RSC Advances, Vol. 6, Núm. 52, pp. 46170-46185
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Topological sub-structural molecular design (TOPS-MODE): a useful tool to explore key fragments of human A3adenosine receptor ligands
Molecular Diversity, Vol. 20, Núm. 1, pp. 55-76
2015
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New platelet aggregation inhibitors based on pyridazinone moiety
European Journal of Medicinal Chemistry, Vol. 94, pp. 113-122
2011
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Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors
Journal of Medicinal Chemistry, Vol. 54, Núm. 20, pp. 7127-7137
2010
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New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities
Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 22, pp. 6624-6627
2007
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ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds
European Journal of Medicinal Chemistry, Vol. 42, Núm. 5, pp. 580-585
2006
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Synthesis and anti-HIV activity of novel cyclopentenyl nucleoside analogues of 8-azapurine
Chemical and Pharmaceutical Bulletin, Vol. 54, Núm. 10, pp. 1418-1420
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Synthesis of 1,2-disubstituted carbocyclic nucleoside analogues of cytidine
Helvetica Chimica Acta, Vol. 89, Núm. 5, pp. 954-961
2005
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1,2-Disubstituted cyclohexane nucleosides: Comparative study for the synthesis of cis and trans adenosine analogues
Tetrahedron, Vol. 61, Núm. 2, pp. 473-478
2004
2002
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Novel 1,2-disubstituted carbocyclic nucleoside analogues of purine with a cyclopentene ring
Synthesis, pp. 2445-2449
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Synthesis and structure-activity relationships of new arylpiperazines: Para substitution with electron-withdrawing groups decrease binding to 5-HT1A and D2A receptors
European Journal of Medicinal Chemistry, Vol. 37, Núm. 6, pp. 503-510
2001
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Synthesis and structural study of pyrimidyl carbocyclic analogues of nucleosides based on cyclopentene rings
Nucleosides, Nucleotides and Nucleic Acids, Vol. 20, Núm. 4-7, pp. 999-1002