Publicacións en colaboración con investigadores/as de Universidade de Santiago de Compostela (38)

2024

  1. Stilbene-pyridazinone hybrids: design, synthesis and in vitro antiplatelet activity screening

    Bioorganic Chemistry, Vol. 150

2022

  1. Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents

    Molecules, Vol. 27, Núm. 23

  2. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity

    ACS Medicinal Chemistry Letters, Vol. 13, Núm. 3, pp. 463-469

2021

  1. Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors

    Bioorganic Chemistry, Vol. 115

2020

  1. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy

    Bioorganic Chemistry, Vol. 104

2019

  1. Novel compounds of hybrid structure pyridazinone-coumarin as potent inhibitors of platelet aggregation

    Future medicinal chemistry, Vol. 11, Núm. 16, pp. 2051-2062

2017

  1. Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

    European Journal of Medicinal Chemistry, Vol. 139, pp. 1-11

2016

  1. Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2: H)-one derivatives as novel cholinesterase inhibitors

    RSC Advances, Vol. 6, Núm. 52, pp. 46170-46185

  2. Topological sub-structural molecular design (TOPS-MODE): a useful tool to explore key fragments of human A3adenosine receptor ligands

    Molecular Diversity, Vol. 20, Núm. 1, pp. 55-76

2015

  1. New platelet aggregation inhibitors based on pyridazinone moiety

    European Journal of Medicinal Chemistry, Vol. 94, pp. 113-122

2011

  1. Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors

    Journal of Medicinal Chemistry, Vol. 54, Núm. 20, pp. 7127-7137

2010

  1. New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities

    Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 22, pp. 6624-6627

2007

  1. ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds

    European Journal of Medicinal Chemistry, Vol. 42, Núm. 5, pp. 580-585

2006

  1. Synthesis and anti-HIV activity of novel cyclopentenyl nucleoside analogues of 8-azapurine

    Chemical and Pharmaceutical Bulletin, Vol. 54, Núm. 10, pp. 1418-1420

  2. Synthesis of 1,2-disubstituted carbocyclic nucleoside analogues of cytidine

    Helvetica Chimica Acta, Vol. 89, Núm. 5, pp. 954-961

2005

  1. 1,2-Disubstituted cyclohexane nucleosides: Comparative study for the synthesis of cis and trans adenosine analogues

    Tetrahedron, Vol. 61, Núm. 2, pp. 473-478

2004

  1. A short and convenient synthesis of new 1,2-disubstituted carbocyclic nucleoside analogues of pyrimidine based on a cyclopentene ring

    Synthesis, pp. 543-548

2002

  1. Novel 1,2-disubstituted carbocyclic nucleoside analogues of purine with a cyclopentene ring

    Synthesis, pp. 2445-2449

  2. Synthesis and structure-activity relationships of new arylpiperazines: Para substitution with electron-withdrawing groups decrease binding to 5-HT1A and D2A receptors

    European Journal of Medicinal Chemistry, Vol. 37, Núm. 6, pp. 503-510

2001

  1. Synthesis and structural study of pyrimidyl carbocyclic analogues of nucleosides based on cyclopentene rings

    Nucleosides, Nucleotides and Nucleic Acids, Vol. 20, Núm. 4-7, pp. 999-1002